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Spatial mapping of the human maternal fetal interface: a normative template for vascular remodeling and immune tolerance

Little is known about the regulation of the maternal immune response to the fetus. The Angelo Lab aims to use this MIBI to delineate immune cell populations and their spatial organization in order to reveal the pathways that lead to spiral artery remodeling and induction of the regulatory immune response to the fetus. In addition to addressing a basic question in reproductive biology - why does the maternal immune system not attack the fetus - this research also aims to address obstetric complications related to immunological responses such as preeclampsia and preterm birth. Join this MCHRI seminar to learn more!

Speakers & Topics:
Michael Angelo, MD, PhD, Assistant Professor of Pathology
High dimensional imaging platform and imaging human decidua in the first 20 weeks of pregnancy

Ke Leow, Graduate student
Recent data on maternal fetal glycosylation

May 2, 2022 12:00 PM in Pacific Time (US and Canada)